Don Brown
Precision Medicine vs Precision Health vs Hyper Wellbeing – EP05: Don Brown (LifeOmic)
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In this fifth episode, Don Brown, CEO LifeOmic, explains the nomenclature shift from precision medicine to precision health, details the firm footing his company has in precision health, how it’s now extending another foot forwards into hyper wellbeing. Lots of app, lifestyle medicine, lifespan, healthspan and biological age quantification chat.
Topics we discussed in this episode
- Precision medicine vs precision health
- Storage of panoramic health data/longitudinal datasets
- Intermittent fasting
- Institutional top-down and emerging bottom-up direct-to-consumer approaches to health
- Precision health vs hyper wellbeing
- Need to focus on aging itself as root cause of most diseases
- Homeostasis
- Healthspan vs lifespan
- Lifestyles that accelerate aging
- Lifestyles that decelerate aging
- Biological age quantification
- Using an app to decelerate aging, extend lifespan and increase healthspan
- High insulin as age accelerator
- Evolutionary medicine as age decelerator
- Machines as overlords vs machines as health companions
- Precision lifestyles guided by machines
- Healthcare set for exponential changes ahead
- Lack of nutritional training in medical school
- Tendency of healthcare institutions to hoard data and doctors trained to limit data gathered
- Hormesis
- Our biological avatar models running in the cloud
- Orthomolecular medicine and triage theory
- In app integration of genomics, microbiome and other tests
- In app gamification of “healthy living”
- Mindfulness
- Glucose ketone index
- Tying lifestyle changes to rate of biological aging to change behavior
- Nicotinamide adenine dinucleotide (NAD) and other supplements
Show links
- LifeOmic Website
- LifeOmic Fasting Tracker for iOS Download
- LIFE: The Socially-Connected Intermittent Fasting App that Leverages Precision Medicine Blog Article
- A Vision of LIFE Extend — A Powerful Precision Health Mobile App Blog Article
- LIFE Extend – Pre-Registration Web Page
- Epigenetic Clock Wikipedia Entry
- DNA Methylation Age of Human Tissues and Cell Types Paper
- DNA Methylation-Based Biomarkers and the Epigenetic Clock Theory of Ageing Paper
- Hormesis Wikipedia Entry
- Antagonistic Pleiotropy Hypothesis Wikipedia Entry
- myDNAge Website
- Life Length Website
- Effects of Longevinex (Modified Resveratrol) on Cardioprotection and its Mechanisms of Action Paper
- Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer Book
- Warburg Effect Wikipedia Entry
- Hyper Wellbeing Episode #002 – L-Nutra’ Joseph Antoun on Fasting Mimicking Diets, Biological Aging and Longevity
- Juvenescence: Investing in the Age of Longevity Book
- An Epigenetic Biomarker of Aging for Lifespan and Healthspan Paper
- Methylation Aging Clock: An Update Blog Article
- Steve Horvath Wikipedia Entry
- Slowing Ageing by Design: the Rise of NAD+ and Sirtuin-Activating Compounds Paper
- Sirtuin Wikipedia Entry
- David Sinclair’s Beginner’s Guide to Anti-Ageing News Article
- Triage Theory Paper
- Orthomolecular Medicine Wikipedia Entry
- What is Glucose Ketone Index Blog Article
- Glucose Ketone Index (GKI) Calculator
- What is Tokenomics and How it Can Make or Break your ICO
- Elysium Health Website
- Longevinex Website
- Leonard P Guarente Wikipedia Entry